✦ LIBER ✦

Long-lived plasma cells: a mechanism for maintaining persistent antibody production

✍ Scribed by Mark K Slifka; Rafi Ahmed

Book ID: 104358908
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 582 KB
Volume: 10
Category: Article
ISSN: 0952-7915
DOI: 10.1016/s0952-7915(98)80162-3

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✦ Synopsis

Current models suggest that continuous antigenic stimulation of memory B cells is required to maintain long-term antibody production. In view of recent developments concerning plasma cell longevity, a new model is described that incorporates the important role of long-lived plasma cells in sustaining persistent antibody responses.

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