## Abstract The transition from adolescence to adulthood is accompanied by substantial plastic modifications in the cerebral cortex, including changes in the growth and retraction of neuronal processes and in the rate of synaptic formation and neuronal loss. Some of these plastic changes are preven
β¦ LIBER β¦
Long-acting insulin analogues elicit atypical signalling events mediated by the insulin receptor and insulin-like growth factor-I receptor
β Scribed by E. Yehezkel; D. Weinstein; M. Simon; R. Sarfstein; Z. Laron; H. Werner
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 408 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0012-186X
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## Insulin -like growth factors (IGFs) are potent proliferation stimulators for numerous tumor cells and often function as autocrine growth factors. We have previously shown that exogenous IGF-I and IGF-II enhance proliferation of colorectal carcinoma cells. The biological signal of both factors i