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Lone-pair cooperativity in the N-alkylation of some derivatives of 2,2'-biimidazole

✍ Scribed by Deady, LW


Book ID
125441412
Publisher
Commonwealth Scientific and Industrial Research Organisation Publishing
Year
1981
Tongue
English
Weight
421 KB
Volume
34
Category
Article
ISSN
0004-9425

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The role of the nitrogen lone pairs in the mechanism of the acid-catalysed epimerization of indolo[2,3-a]quinolizidines is investigated using laetams as model compounds. Deethylebumamonine (3) did not epimerize with trifluoroacetic acid (TFA), whereas deethyldihydroeburnamenine (7) underwent epimeri