## Abstract Activating mutations of __RAS__ gene families have been found in a variety of human malignancies, including lung cancer, suggesting their dominant role in tumorigenesis. However, several studies have shown a frequent loss of the wildβtype __KRAS__ allele in the tumors of murine models a
LOH of chromosome 12p correlates with Kras2 mutation in non-small cell lung cancer
β Scribed by Li, Jie; Zhang, Zhongqiu; Dai, Zunyan; Plass, Christoph; Morrison, Carl; Wang, Yian; Wiest, Jonathan S; Anderson, Marshall W; You, Ming
- Book ID
- 110067313
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 136 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The optimal management of patients with nonsmall cell lung cancer (NSCLC) depends on the accuracy of appropriate staging strategies. The best approach for clinical staging, especially the evaluation of lymph node metastasis, continues to confound clinicians. A specific, less-invasive method to suppo
## Abstract LINEβ1 and Alu elements are nonβLTR retrotransposons, constituting together over 30% of the human genome and they are frequently hypomethylated in human tumors. A relationship between global hypomethylation and genomic instability has been shown, however, there is little evidence to sug