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Logistic transmission modeling of simulated data

โœ Scribed by Dr. John B. Harley; Kathy L. Moser; Barbara R. Neas

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
386 KB
Volume
12
Category
Article
ISSN
0741-0395

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โœฆ Synopsis

A nonparametric method for linkage analysis has been developed and applied to the Problem 1 data set of the Genetic Analysis Workshop 9. Basically, the univariate matched pair strategy of the transmission disequilibrium test has been adapted to multivariate modeling using the conditional logistic function. After setting the critical value for significance at p i 0.0001, models at only D5G23 and DIG3 1 appear to be significant (p < Logistic transmission modeling is a powerful method for establishing linkage by disequilibrium.

1995 WiIey-Liss, Inc.

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