Log-normal distribution for a description of the molecular weight distribution of N-acetylated chitosans depolymerized with hydrolytic enzyme

✍ Scribed by Dr Yoshitsune Shin-ya; Toru Yoshizawa; Kyung-Jin Hong; Moo-Yeal Lee; Toshio Kajiuchi

• Publisher: John Wiley and Sons
• Year: 2003
• Tongue: English
• Weight: 112 KB
• Volume: 52
• Category: Article
• ISSN: 0959-8103
• DOI: 10.1002/pi.1182

✦ Synopsis

Abstract

N‐acetylated chitosans (NACs) with different degrees of N‐acetylation (DAs) were enzymatically depolymerized at pH 5.1 and 40 °C, and the molecular weight distributions (MWDs) of the depolymerized NACs were then measured by size exclusion chromatography and were fitted by the log‐normal distribution function with two distribution parameters, β and M~0~. We discuss also the time‐evolution of the distribution parameters derived from the experimentally obtained MWD as well as the effects of experimental conditions, such as DA and initial NAC concentration (S~0~), on the distribution parameters. Copyright © 2003 Society of Chemical Industry