The log-linear model is modified in order to adapt i t t o the disease-genotype association problem, where two loci are involved. By so doing, the structure of associations among the genetic variables can be determined, and sources of distortion can be identified in certain test statistics and coeff
Log-linear model analysis of allelic associations
โ Scribed by C. E. Aston; S. R. Wilson; D. C. Rao
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 376 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0741-0395
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โฆ Synopsis
An approach is outlined for the analysis of nonrandom allelic associations in multilocus systems in a diploid population. The concept of composite link functions in generalised linear model analysis is used to handle the problem of incomplete identification of constituent gametes often encountered in genotypic data for two or more marker loci.
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