Extensive allelic sequence variation in
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Petri S. Mattila; Jan Schugk; Hongyan Wu; Olli Mäkelä
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Article
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1995
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John Wiley and Sons
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English
⚖ 638 KB
During the initial stages of B lymphocyte differentiation heavy chain variable (VH), diversity (DH) and joining (JH) gene segments recombine to form a functional heavy chain variable region (VDJ) gene. Evidence for genetic polymorphism of the human JH gene segments has been obtained from mature rear