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Locomotor disturbances in rats induced by repeated picrotoxin microinjections to the globus pallidus and caudal neostriatum

✍ Scribed by A. F. Yakimovskii


Publisher
Springer US
Year
1998
Tongue
English
Weight
208 KB
Volume
126
Category
Article
ISSN
0007-4888

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## Abstract Symptoms in the early stages of Huntington's disease (HD) are assumed to reflect basal ganglia circuit dysfunction secondary to degeneration of striatal projections to the external segment of the globus pallidus (GPe). The hypothesis that GPe lesion would ameliorate HD symptoms by β€œnorm