✦ LIBER ✦
Location of a gene conferring DDT resistance but no pyrethroid cross-resistance in larvae ofAnopheles stephensi
✍ Scribed by C. A. Malcolm
- Book ID
- 104624977
- Publisher
- Springer Netherlands
- Year
- 1990
- Tongue
- English
- Weight
- 357 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0016-6707
No coin nor oath required. For personal study only.
✦ Synopsis
In larvae of Anopheles stephensi, DDT resistance of 30 to 40-fold, involving no cross-resistance to pyrethroids, showed fully dominant monofactorial inheritance. The gene, termed DDT, is located 36.6 cross-over units from the morphological mutant, black larvae (BI), on chromosome III. A polygenic system, which confers a 17-fold reduction in susceptibility to knockdown by the pyrethroid, permethrin, also makes a minor contribution to DDT resistance. It was not possible to block DDT resistance with the dehydrochlorinase inhibitor DMC.