Distinct patterns of germ-line deletions
β
Lili Li; Susan McVety; Rami Younan; Ping Liang; DesirΓ©e Du Sart; Philip H. Gordo
π
Article
π
2006
π
John Wiley and Sons
π
English
β 169 KB
π 2 views
A relatively high frequency of germ-line genomic rearrangements in MLH1 and MSH2 has been reported among Lynch Syndrome (HNPCC) patients from different ethnic populations. To investigate the underlying molecular mechanisms, we characterized the DNA breakpoints of 11 germ-line deletions, six for MLH1