Localized T2 measurements using an OSIRIS–CPMG method. Application to measurements of blood oxygenation and transverse relaxation free of diffusion effect
✍ Scribed by F. Girard; P. Poulet; I. J. Namer; J. Steibel; J. Chambron
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 694 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0952-3480
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✦ Synopsis
This work presents a new method allowing localized T2 measurements, based upon the OSIRIS scheme. A train of 180" pulses is applied after the OSIRIS preparation cycle, recording directly the transverse magnetization decay. The method was verified for two nuclei, 'H and '9, with phantoms and in uiuo on rats. The accuracy of the T2 values is discussed, as well as possible applications of the OSIRIS-CPMG method to proton transverse spin relaxation measurements, free of diffusion effects, and to non-invasive in uiuo blood oxygenation measurements, lhrough the use of an emulsion of perfluorooctylbromide, a blood substitute containing fluorine.