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Localized role of CRMP1 and CRMP2 in neurite outgrowth and growth cone steering

โœ Scribed by Masakazu Higurashi; Masumi Iketani; Kohtaro Takei; Naoya Yamashita; Reina Aoki; Nobutaka Kawahara; Yoshio Goshima


Book ID
115555107
Publisher
Wiley (John Wiley & Sons)
Year
2012
Tongue
English
Weight
894 KB
Volume
72
Category
Article
ISSN
1932-8451

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The controlled extension of neurites is essential not only for nervous system development, but also for effective nerve regeneration after injury. This process is critically dependent on microtubule assembly since axons fail to elongate in the presence of drugs which disrupt normal assembly dynamics