Localization study of co-phthalocyanines in cells by Raman micro(spectro)scopy
✍ Scribed by S. Y. Arzhantsev; A. Y. Chikishev; N. I. Koroteev; J. Greve; C. Otto; N. M. Sijtsema
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 256 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0377-0486
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✦ Synopsis
An investigation of intracellular localization of Co-phthalocyanines is reported. The Raman images of K562 cells stained with phthalocyanine were acquired. To understand the peculiarities of the Raman images, measurements were performed at di †erent z-axis positions. The intracellular concentration of phthalocyanine was estimated. A colocalization study was carried out using the Ñuorescence probes FITC-dextran and acridine orange by means of Raman and Ñuorescence microscopy. Partial colocalization with both probes was revealed. Copyright John ( 1999 Wiley & Sons, Ltd.