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Localization, sequence analysis, and ethnic distribution of a 96-bp insertion in the promoter of the human CYP2E1 gene

✍ Scribed by Ellen Fritsche; Gary S Pittman; Douglas A Bell


Book ID
117768012
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
691 KB
Volume
432
Category
Article
ISSN
1383-5726

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## Abstract To better understand the molecular mechanisms of cytochrome P450 1A2 (__CYP1A2__) regulation, we have characterized a region of the promoter (+3 to βˆ’176) that contains a single E‐box and an adjacent nuclear factor 1 (NF1)‐like DNA binding site. The E‐box was shown to specifically bind n