The presence of spinning sidebands can severely compromise pression will not be used, the first criterion is satisfied. the detection of low molarity analytes. Spinning sidebands have Modern NMR spectrometers, appropriately configured, traditionally been minimized by improving the magnetic field hoh
Localization of unaffected spins in NMR imaging and spectroscopy (LOCUS spectroscopy)
β Scribed by Axel Haase
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 325 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
β¦ Synopsis
A new method for the localization of N M R spectra in vivo is presented. Herein a series of selective 90" pulses with different camer frequencies in the presence of magnetic field gradients is saturating spins of unwanted regions. Only spins in the region of interest are left unaffected. The LOCUS (localization of unaffected spins) spectrum of this region is measured by a single 90" excitation pulse. The FLASH imaging sequence combined with the LOCUS technique allows the identification of the region of interest. o 1986 Academic Press, Inc.
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## Abstract In a previous work (1), the susceptibility broadening in the ^1^H NMR metabolite spectrum obtained in a live mouse was separated from the isotropic information, which significantly increased the spectral resolution. This was achieved using ultraslow magic angle spinning (MAS) of the ani