Localization of the X inactivation centre on the human X chromosome in Xq13
โ Scribed by Brown, Carolyn J.; Lafreniere, Ronald G.; Powers, Vicki E.; Sebastio, Gianfranco; Ballabio, Andrea; Pettigrew, Anjana L.; Ledbetter, David H.; Levy, Elaine; Craig, Ian W.; Willard, Huntington F.
- Book ID
- 109766878
- Publisher
- Nature Publishing Group
- Year
- 1991
- Tongue
- English
- Weight
- 527 KB
- Volume
- 349
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/349082a0
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In three women with a 46,XXq- chromosome constitution, the length of the deletion was expressed as the ratio of the remaining part of Xq to Xp c' over a + b. In one of them (KH) this ratio was 0.33, in another (GE) 0.59, and in the third (AP) the ratio fell between these values. The break in KH is m
## Location of an X-inactivation Centre in Mouse and Human Experiments utilising X-autosome translocations in or autosomal insertions into X chromosome material(") indicated that autosomal coat colour genes placed adjacent to X chromosome material could be inactivated resulting in coat colour vari