Localization of the inosine triphosphatase locus (Itp) on chromosome 2 of the mouse

✍ Scribed by Benjamin A. Taylor; Donna M. Walls; Michael J. Wimsatt

• Publisher: Springer
• Year: 1987
• Tongue: English
• Weight: 403 KB
• Volume: 25
• Category: Article
• ISSN: 0006-2928
• DOI: 10.1007/bf00499320

✦ Synopsis

An electrophoretic variant of the enzyme inosine triphosphatase was found by screening inbred strains of mice. Strains with the slower-migrating variant include BALB/cJ, DBA/1J, and PL/J. The Itp locus was mapped between the beta-2-microglobulin (B2m) and the agouti (a) loci on chromosome 2. The mapping of Itp on chromosome 2 identifies a chromosomal segment that has been conserved since the divergence of lineages leading to mouse and man.