The human cytidine-5'-triphosphate synthetase (CTPS) gene was mapped by a direct mapping system combined with fluorescence in situ hybridization and replicated prometaphase R-bands. By high-resolution banding analysis, the signals were localized to band 34.1-34.3 of the short arm of chromosome 1; 1p
Localization of the human Rh blood group gene structure to chromosome region 1p34.3–1p36.1 by in situ hybridization
✍ Scribed by B. Chérif-Zahar; M. G. Mattéi; C. Kim; P. Bailly; J. -P. Cartron; Y. Colin
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 469 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0340-6717
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✦ Synopsis
A cDNA clone, RhIXb (1384bp), encoding the entire protein sequence of a human blood group Rh polypeptide has been used to map the Rh locus, by in situ hybridization, to the region p34.3-p36.1 of chromosome 1. Two other unrelated cDNA clones, pUCA2 (750bp) and pUCIII (1600 bp), isolated during the cloning procedure of the Rh cDNA were investigated simultaneously, and assigned to chromosome 3p21.1-3p22 (clone pUCA2) and to chromosome 22q12.1-22q13.1 (clone pUCIII).
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