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Localization of the Fission Yeast U5.U2/U6 Spliceosome Subunits

โœ Scribed by Takizawa, Yoshimasa; Ohi, Melanie D.

Book ID
122192085
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
31 KB
Volume
98
Category
Article
ISSN
0006-3495

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We are applying a genetic approach toward understanding the mechanism and structural significance of the dynamic change in behavior of the U4/U6 and U5 snRNPs during splicing. We have postulated previously that U4 and U6 are tightly associated via an extensive hydrogen-bonding interaction (Brow and