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Localization of the chromosomal breakpoints of the t(12;16) in liposarcoma to subbands 12q13.3 and 16p11.2

✍ Scribed by Magnus Eneroth; Nils Mandahl; Sverre Heim; Helena Willén; Anders Rydholm; Karl Akke Alberts; Felix Mitelman

Book ID
119104740
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
323 KB
Volume
48
Category
Article
ISSN
0165-4608

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Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11)
✍ Dr. Pierre Åman; David Ron; Nils Mandahl; Thoas Fioretos; Sverre Heim; Kristina 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 809 KB

Most myxoid liposarcomas (MLS) are characterized cytogenetically by a t( 12; I6)(q I3:p I I). It is reasonable t o assume that this translocation corresponds t o the consistent rearrangement of one o r t w o genes in 12q I 3 and/or I6p I I, and that the loci thus affected are important in the normal