Localization of the Bf locus within the HLA region

✍ Scribed by Ch. Rittner; H. Grosse-Wilde; E. D. Albert

• Book ID: 104709743
• Publisher: Springer
• Year: 1976
• Tongue: English
• Weight: 238 KB
• Volume: 35
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00295621

✦ Synopsis

Since the estimation of recombination fractions is only an arbitrary means to map genetic loci on chromosomal regions, family studies of cases with informative cross-overs within the region in question are of decisive importance. This paper reports the study of a family with a HLA-B to HLA-D cross-over which is informative in the Bf system. The possible reasons for conflicting published data on Bf gene mapping are discussed.