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Localization of the Bf locus within the HLA region

โœ Scribed by Ch. Rittner; H. Grosse-Wilde; E. D. Albert


Book ID
104709743
Publisher
Springer
Year
1976
Tongue
English
Weight
238 KB
Volume
35
Category
Article
ISSN
0340-6717

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โœฆ Synopsis


Since the estimation of recombination fractions is only an arbitrary means to map genetic loci on chromosomal regions, family studies of cases with informative cross-overs within the region in question are of decisive importance. This paper reports the study of a family with a HLA-B to HLA-D cross-over which is informative in the Bf system. The possible reasons for conflicting published data on Bf gene mapping are discussed.


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