𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Localization of the amino acid substitution site in a fast migrating variant of human serum albumin

✍ Scribed by P. ladarola; L. Minchiotti; M. Galliano

Book ID
115916636
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
312 KB
Volume
180
Category
Article
ISSN
0014-5793

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

In vitro stereoselective degradation of
In vitro stereoselective degradation of carprofen glucuronide by human serum albumin. Characterization of sites and reactive amino acids
✍ HΓ©lΓ¨ne Georges; Nathalie Presle; Thierry Buronfosse; Sylvie Fournel-Gigleux; Pat πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 202 KB

Acyl glucuronides formed from carboxylic acids can undergo hydrolysis, acyl migration, and covalent binding to proteins. In buffers at physiological pH, the degradation of acylglucuronide of a chiral NSAID, carprofen, consisted mainly of acyl migration. Acidic pH reduced hydrolysis and acyl migratio