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Localization of protein kinase C alpha isoform expression in the normal human gastrointestinal tract. Comparison with colorectal cancer


Book ID
123396235
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
143 KB
Volume
108
Category
Article
ISSN
0016-5085

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## Abstract Previous studies have suggested that protein kinase C (PKC) may play an important role in colon carcinogenesis and that human colon tumors have less total PKC enzyme activity than normal tissue. Because PKC is a multigene family that enocodes for at least 11 distinct isofroms, in the st