## Abstract Isolated mental retardation is clinically and genetically heterogenous and may be inherited in an autosomal dominant, autosomal recessive, or X‐linked manner. We report here a linkage analysis in a large family including 15 members, 6 of whom presenting X‐linked non‐syndromic mental ret
Localization of MRX82: A new nonsyndromic X-linked mental retardation locus to Xq24-q25 in a Basque family
✍ Scribed by Francisco Martínez; Isabel Martínez-Garay; Silvestre Oltra; María Dolores Moltó; Carmen Orellana; Sandra Monfort; Félix Prieto; Isabel Tejada
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 99 KB
- Volume
- 131A
- Category
- Article
- ISSN
- 1552-4825
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📜 SIMILAR VOLUMES
Nonspecific X-linked mental retardation is a heterogeneous condition consisting of nonsyndromal mental retardation in males. It is caused by mutation in one of several genes on the X chromosome (MRX genes). Here we report on the localization of a presumptive MRX gene to chromosomal region Xq24-q26 i
Families with mentally retarded males found to be negative for FRAXA and FRAXE mutations are useful in understanding the genetic basis of X-linked mental retardation. According to the most recent data (updated to 1999), 69 MRX loci have been mapped and 6 genes cloned. Here we report on a linkage stu