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Localization of cyclooxygenase isozymes in cardiovascular tissues of dogs treated with naproxen

โœ Scribed by Kristina M. Stanfield; K.Nasir Khan; Michael R. Gralinski


Book ID
117335797
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
685 KB
Volume
80
Category
Article
ISSN
0165-2427

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The pharmacokinetic profiles of naproxen in blood and synovial fluid (SF) following topical and i.v. bolus administration in dogs, and the local tissue disposition of the drug following topical and oral administration in rats, were investigated to assess the feasibility of topical delivery of naprox