The combination of the new photodynamic sensitizer 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) and laser light of wavelength 665 nm showed antitumor activity against two s.c.-implanted murine tumors. HPPH also sensitized normal mouse foot tissue to light but photosensitivity decreased ra
β¦ LIBER β¦
Localization and treatment of transformed tissues using the photodynamic sensitizer 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a
β Scribed by Furukawa, Kinya; Yamamoto, Hideki; Crean, David H.; Kato, Harubumi; Mang, Thomas S.
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 1000 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0196-8092
No coin nor oath required. For personal study only.
β¦ Synopsis
Furukawa et al. Conclusions: It appears that HPPH may be a promising photosensitizer for the detection and photodynamic treatment of transformed tissues. o 1996 Wiley-Liss, Inc.
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## Abstract ## Background and Objectives Photodynamic therapy (PDT) uses a photosensitizer activated by light, in an oxygenβrich environment, to destroy malignant tumors. Clinical trials of PDT at Roswell Park Cancer Institute (RPCI) use the photosensitizers Photofrin, Photochlor, and 5βALAβinduce