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Local self-assembly mechanisms underlie the differential transformation of the proximal and distal cut axonal ends into functional and aberrant growth cones

✍ Scribed by Hadas Erez; Micha E. Spira

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 336 KB
Volume: 507
Category: Article
ISSN: 0021-9967
DOI: 10.1002/cne.21637

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✦ Synopsis

Abstract

Following axotomy both the proximal and distal cut axonal ends transform into growth cones. Whereas the growth cone formed by the tip of the proximal segment branch to form neurites (left hand side), the structure formed by the distal cut end fails to grow. In red‐ microtubules, blue ‐ vesicles, and green ‐ actin. J. Comp. Neurol. 507:1019–1030, 2008. © 2008 Wiley‐Liss, Inc.

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Local Self-Assembly Mechanisms Underlie the Differential Transformation of the Proximal and Distal Cut Axonal Ends Into Functional and Aberrant Growth Cones

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## Abstract Following axotomy both the proximal and distal cut axonal ends transform into growth cones. Whereas the growth cone formed by the tip of the proximal segment branch to form neurites (left hand side), the structure formed by the distal cut end fails to grow. In redmicrotubules, blue ‐ ve