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Local Propensities and Statistical Potentials of Backbone Dihedral Angles in Proteins

โœ Scribed by Marcos R. Betancourt; Jeffrey Skolnick


Book ID
116661471
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
811 KB
Volume
342
Category
Article
ISSN
0022-2836

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## Abstract We have investigated protein conformation sampling and optimization based on the genetic algorithm and discrete main chain dihedral state model. An efficient approach combining the genetic algorithm with local minimization and with a niche technique based on the sharing function is prop