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Local Estimation of Age-Dependent Variance Components from Longitudinal Twin Data

✍ Scribed by Richard Huggins

Book ID: 110724745
Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 759 KB
Volume: 56
Category: Article
ISSN: 0006-341X
DOI: 10.1111/j.0006-341x.2000.00537.x

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## Abstract In diseases caused by deleterious gene mutations, knowledge of age‐specific cumulative risks is necessary for medical management of mutation carriers. When pedigrees are ascertained through several affected persons, ascertainment bias can be corrected by using a retrospective likelihood