Local Anesthetics of the Amino Alkyl Benzoates.*
β Scribed by Lynn, E.V. ;Lofgren, F.V.
- Publisher
- Elsevier
- Year
- 1925
- Weight
- 238 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0898-140X
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Hydrophobicity, a term used to describe a fundamental physicochemical property of local anesthetics, was in the past obtained by octanol/buffer partitioning. It has been suggested that the octanol method, despite its obvious advantages, also has some drawbacks. HPLC has become an attractive alternat
Isonipecaine, an isonipecotic acid derivative (l-methyl-4-phenylpiperidine-4-carboxylic acid ethyl ester hydrochloride), was found to possess considerable local anesthetic properties. I n the discussion of the results, the structural relationships of isonipecaine are compared with those of atropine,
## Abstract Review: 39 refs.