Local anesthetic activity and acute toxicity of N-heptyl-1,2,3,4-tetrahydro-6-methoxy-1-naphthylamine methanesulfonate
β Scribed by Barbara A. Bopp; Anthony T. Dren; Donn M. Ebert; Adolph O. Geiszler
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 313 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3549
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This paper is concerned with the local anesthetic activity and acute toxicity of (+~)-2-(N-ethylpropylamino)-2',6'-butyroxylidide (I). Testing in rat sciatic nerve blocks and guinea pig intradermal wheals showed that the compound has rapid onset, excellent frequency, and long durations of block. The
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