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Liver X Receptor and Farnesoid X Receptor as Therapeutic Targets

✍ Scribed by Daniel J. Rader

Book ID
113444342
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
739 KB
Volume
100
Category
Article
ISSN
0002-9149

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Organic anion transporting polypeptide 1B1 (OATP1B1) is a liver-enriched transporter involved in the hepatocellular uptake of many endogenous molecules and several structurally divergent drugs in clinical use. Although OATP1B1 coding region polymorphisms are known to make an impact on substrate drug