Orthotopic liver transplantation (OLT) is currently incorporated into the treatment regimens for specific nonhepatocellular malignancies. For patients suffering from early-stage, unresectable hilar cholangiocarcinoma (CCA), OLT preceded by neoadjuvant radiotherapy has the potential to readily achiev
Liver transplantation for non–hepatocellular carcinoma malignancies
✍ Scribed by Gregory J. Gores; Julie K. Heimbach; Charles B. Rosen
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 139 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1527-6465
- DOI
- 10.1002/lt.22145
No coin nor oath required. For personal study only.
✦ Synopsis
Key Points
- Hepatic epithelioid hemangioendothelioma is a rare disease with a variable natural history; current data support liver transplantation for unresectable disease. 2. Anti-vascular endothelial cell growth factor therapy may change the approach to hepatic epithelioid hemangioendothelioma in the future. 3. The role of liver transplantation in the treatment of neuroendocrine tumors remains unclear; more data obtained by standardized approaches are needed for evidence-based decision making. 4. Liver transplantation is curative in highly selected patients with perihilar cholangiocarcinoma when it is combined with neoadjuvant therapy. Liver Transpl 16:S22-S25, 2010. V C 2010 AASLD.
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This study was partially supported by grants UBACYT M055 (Universidad de Buenos Aires) and PICT 06-124 (Agencia Nacional de Promocio´n Cien-tı´fica y Tecnolo´gica).