Liver transplantation for hepatocellular carcinoma
β Scribed by Taketomi, Akinobu ;Soejima, Yuji ;Yoshizumi, Tomoharu ;Uchiyama, Hideaki ;Yamashita, Yo-Ichi ;Maehara, Yoshihiko
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 127 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0944-1166
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Background: Liver transplantation for unresectable hepatocellular carcinoma yields disappointing results. Most cases recur within 2 years, often in the transplanted liver. Methods: A combination of neoadjuvant doxorubicin and orthotopic liver transplantation was used in 20 patients with unresectable
Total hepatectomy plus liver transplantation was performed on 105 patients considered unsuitable for liver resection. Postoperative 5-year actuarial survivals correlated with the pathologic stage of the tumor: stage I 75%, stage II 68%, stage III 52.1%, and stage IVA 11%. The overall 5-year survival