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Liver transplantation for hepatocellular carcinoma

✍ Scribed by Taketomi, Akinobu ;Soejima, Yuji ;Yoshizumi, Tomoharu ;Uchiyama, Hideaki ;Yamashita, Yo-Ichi ;Maehara, Yoshihiko


Publisher
Springer
Year
2008
Tongue
English
Weight
127 KB
Volume
15
Category
Article
ISSN
0944-1166

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Background: Liver transplantation for unresectable hepatocellular carcinoma yields disappointing results. Most cases recur within 2 years, often in the transplanted liver. Methods: A combination of neoadjuvant doxorubicin and orthotopic liver transplantation was used in 20 patients with unresectable

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Total hepatectomy plus liver transplantation was performed on 105 patients considered unsuitable for liver resection. Postoperative 5-year actuarial survivals correlated with the pathologic stage of the tumor: stage I 75%, stage II 68%, stage III 52.1%, and stage IVA 11%. The overall 5-year survival