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Liver metastasis and selectin-mediated adhesion to the sinusoidal endothelium by human colon cancer cells is related to mucin carbohydrate structure

โœ Scribed by R.S. Bresalier; J.C. Byrd; P. Brodt; S.H. Itzkowitz

Book ID
118879818
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
147 KB
Volume
108
Category
Article
ISSN
0016-5085

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Mucin production by human colon cancer cells correlates with liver metastasis in animal models, but it is not known which steps in metastasis depend on specific alterations in mucin synthesis. Clonal variants of cell line LS174T selected for differences in mucin core carbohydrate expression have bee