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Liver laceration associated with severe seizures after living donor liver transplantation

โœ Scribed by Kazushige Sato; Satoshi Sekiguchi; Yorihiro Akamatsu; Naoki Kawagishi; Yoshitaka Enomoto; Takeru Iwane; Akira Sato; Keisei Fujimori; Susumu Satomi


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
153 KB
Volume
12
Category
Article
ISSN
1527-6465

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โœฆ Synopsis


Hemorrhagic complications commonly occur early after liver transplantation (LT), sometimes requiring emergent relaparotomy. However, active bleeding from the liver graft itself is a rare but life-threatening complication after living donor liver transplantation (LDLT). We report an unusual case of liver laceration with massive bleeding, associated with severe epileptic seizures as a result of tacrolimus-induced leukoencephalopathy, after LDLT. The patient was successfully rescued by conventional surgical management without a second transplantation. In conclusion, to our knowledge this is the first reported case of graft rupture due to immunosuppression-associated leukoencephalopathy after LT.


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