An assessment was made of the frequency of liver cell dysplasia and the mean age of each group in 56 normal, 13 cirrhotic, and 50 hepatocellular carcinoma (HCC) patients, 40 with cirrhosis, from southern Africa. Dysplasia increased from 7.1% in normal subjects to 38.5% in cirrhotic, 40% in noncirrho
Liver cell dysplasia and hepatitis B surface antigen in liver cirrhosis and hepatocellular carcinoma
โ Scribed by Go Akagi; Keizo Furuya; Akira Kanamura; Tadao Chihara; Hisashi Otsuka
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 408 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0008-543X
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An analysis of 105 autopsy cases (77 male, 28 female) of hepatocellular carcinoma (HCC) showed that 90 cases (85.7%) were associated with liver cirrhosis, of which 75 cases (83.3%) were of the macronodular type. Hepatitis B surface antigen (HBsAg) was detected with orcein stain in the hepatic tissue
## BACKGROUND. Telomeres, at the ends of eukaryotic chromosomes, are defined functionally as necessary for chromosome stability. Chromosome instability induced in part by loss of telomeric DNA has been considered to play a significant role in the development of human cancers. However, little is kn