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Liver- and lobe-selective gene transfection following the instillation of plasmid DNA to the liver surface in mice

✍ Scribed by Shigeru Kawakami; Ryu Hirayama; Keiko Shoji; Rie Kawanami; Koyo Nishida; Mikiro Nakashima; Hitoshi Sasaki; Toshiyuki Sakaeda; Junzo Nakamura

Book ID
117051912
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
121 KB
Volume
294
Category
Article
ISSN
0006-291X

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## Abstract ## Background To properly study gene expression __in vivo__, often long‐term expression is desired. Previous studies using plasmid DNA (pDNA) vectors have typically resulted in short‐term expression. Here, we evaluated combinations of the albumin promoter with different enhancers and u