treatment of autoimmune and infectious diseases, and organ or bone marrow transplantation. Proposals for the BPRC-LSF will be selected on the basis of scientific merit through an independent peer review procedure. Ethical implications of selected proposals for both programs are evaluated by the Inst
Live attenuated vaccines for human use
โ Scribed by Stanley J. Cryz Jr.
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 557 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0958-1669
No coin nor oath required. For personal study only.
โฆ Synopsis
Live attenuated vaccines have been successfully used for the prevention of a number of viral and bacterial diseases. Several vaccine strains have been utilized recently as expression vectors for cloned heterologous antigens. Through the use of recombinant DNA technology, candidate vaccine strains and vector systems have been developed and are undergoing clinical evaluation.
๐ SIMILAR VOLUMES
A procedure to attenuate live influenza virus of type A and type B was developed using adaptation of the virus to grow at 25 degrees C (cold adaptation; ca). Through a series of stepwise passages, two stable mutants were obtained and designated as 'Master' strains, one for type A influenza virus (A/