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Lithium side effects in relation to brain lithium concentration measured by lithium-7 magnetic resonance spectroscopy

โœ Scribed by Tadafumi Kato; Kumiko Fujii; Toshiki Shioiri; Toshiro Inubushi; saburo Takahashi


Book ID
116120250
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
686 KB
Volume
20
Category
Article
ISSN
0278-5846

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## Abstract The therapeutic mechanism of action of lithium (Li) in bipolar disorder is unknown. While Li is presumed to work intracellularly in the brain, the fraction of intracellular Li in the brain in vivo is not known. It has not yet been possible to determine, directly and noninvasively, the i