Lithium-responsive affective disorders: no association with the tyrosine hydroxylase gene
β Scribed by Patrizia Cavazzoni; Martin Alda; Gustavo Turecki; Guy Rouleau; Eva Grof; Rory Martin; Anne Duffy; Paul Grof
- Book ID
- 116102365
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 602 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0165-1781
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Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the synthesis of 5-hydroxytryptamine (5-HT). An association study in bipolar affective disorder I or unipolar major affective disorder was performed by using a Bfa I restriction site polymorphism within intron 7 of the tryptophan hydroxylas
Tyrosine hydroxylase (TH) is the ratelimiting enzyme in the synthesis of dopamine and norepinephrine. It may be involved in the pathophysiology of psychiatric disorders and positive associations have been reported for TH gene markers in mood disorders. While most replications failed to confirm the i
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