✦ LIBER ✦
Lithium Perchlorate Mediated Allylic Substitution Reaction Using a Cyclohexenyl Based Model System
✍ Scribed by Chase C. Smith; Roger R. Rothhaar; Karla J. Thobe; Cynthia M. Crago; Peter Pekelnicky
- Book ID
- 102618332
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 138 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0026-265X
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✦ Synopsis
A methodology was developed for the direct substitution of allylic alcohols and acetates by alcohol nucleophiles in order to synthesize allylic ethers. The reaction was mediated by highly concentrated ethereal solutions of lithium perchlorate and proceeded with high regiospecificity.