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Lithium Augmentation Increases the ACTH and Cortisol Response in the Combined DEX/CRH Test in Unipolar Major Depression

✍ Scribed by Tom Bschor; Mazda Adli; Christopher Baethge; Uta Eichmann; Marcus Ising; Manfred Uhr; Sieglinde Modell; Heike Künzel; Bruno Müller-Oerlinghausen; Michael Bauer

Book ID
114281024
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
124 KB
Volume
27
Category
Article
ISSN
1470-634X

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✍ Tom Bschor; Christopher Baethge; Mazda Adli; Uta Eichmann; Marcus Ising; Manfred 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 87 KB 👁 1 views

Although considerable evidence exists on the efficacy of lithium as an augmenting agent in refractory depression, the underlying neurobiology of this phenomenon is unknown. In patients with major depression, changes of the hypothalamic-pituitary-adrenocortical (HPA) system have been detected by mean