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Lissencephaly and LIS1: insights into the molecular mechanisms of neuronal migration and development

✍ Scribed by A Wynshaw-Boris

Book ID
110888482
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
221 KB
Volume
72
Category
Article
ISSN
0009-9163

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✍ Carlos Cardoso; Richard J. Leventer; James J. Dowling; Heather L. Ward; June Chu πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 516 KB

Classical lissencephaly (LIS) and subcortical band heterotopia (SBH) are related cortical malformations secondary to abnormal migration of neurons during early brain development. Approximately 60% of patients with classical LIS, and one patient with atypical SBH have been found to have deletions or