## Abstract Previous family and twin studies indicate that genetic variation makes an important contribution to individual variation in high density lipoprotein cholesterol (HDL) levels, even after adjustment for covariates (such as obesity and alcohol consumption) that also cluster in families. Ho
β¦ LIBER β¦
LISREL modeling of high density lipoprotein cholesterol (HDL) levels in male twins
β Scribed by Dr. Joseph E. Schwartz; Huixing Yuan; Nancy R. Mendell; Stephen J. Finch
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 281 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0741-0395
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β¦ Synopsis
Abstract
Based on the LISREL modeling approach for data from monozygotic (MZ) and dizygotic (DZ) twins [Heath et al., 1989; Neale and Cardon, 1992], the hypothesized variance of the logarithm of high density lipoprotein cholesterol due to additive genetic factors was estimated to equal 19% for males. Unobserved common environment accounted for 32% of the variance of log HDL. Both estimates controlled for body mass, alcohol consumption, and smoking. The model had very strong goodnessβofβfit indices. Β© 1993 WileyβLiss, Inc.
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