Liquid—Solid extraction of lyophilized biological material for forensic analysis : I. Application to urine samples for detection of drugs of abuse

✍ Scribed by J.R. Broich; D.B. Hoffman; S.J. Goldner; S. Andryauskas; C.J. Umberger

• Publisher: Elsevier Science
• Year: 1971
• Tongue: English
• Weight: 404 KB
• Volume: 63
• Category: Article
• ISSN: 1873-3778
• DOI: 10.1016/s0021-9673(01)85643-0

✦ Synopsis

A new method is described for the detection of drugs of abuse in urine, based on the techniques of lyophilization and liquid-solid extraction.

Urine samples are acidified with acetic acid and then freeze-dried.

The residues are then estracted and the extracts subjected to thin-layer chromatography.

The method achieves much greater recovery of all classes of compounds than standard estraction procedures.

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