Liquid-phase combinatorial reaction monitoring by conventional 1H NMR spectroscopy
β Scribed by Jing-Ying Shey; Chung-Ming Sun
- Book ID
- 104250488
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 123 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The application of 1 H NMR spectroscopy for complete analysis of soluble polymer-supported reactions is described. This conventional analytical technique enables us to determine the extent of liquid-phase reactions without cleavage of the soluble matrix. The polymer matrix permitted us to obtain 1 H NMR spectra with a resolution comparable with that of spectra of the molecule in solution.
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