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Liquid chromatography–tandem mass spectrometry for the identification of l-tetrahydropalmatine metabolites in Penicillium janthinellum and rats

✍ Scribed by Li Li; Min Ye; Kaishun Bi; Dean Guo


Book ID
102773350
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
585 KB
Volume
20
Category
Article
ISSN
0269-3879

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✦ Synopsis


Identification of l-tetrahydropalmatine metabolites 95 ORIGINAL RESEARCH


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✍ Peng Li; Guang-Ji Wang; Jing Li; Hai-Ping Hao; Chao-Nan Zheng 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 409 KB

## Abstract The metabolism of tanshinone IIA was studied in rats after a single‐dose intravenous administration. In the present study, 12 metabolites of tanshinone IIA were identified in rat bile, urine and feces with two LC gradients using LC‐MS/MS. Seven phase I metabolites and five phase II meta