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Liquid Chromatography/Tandem Mass Spectrometry Detection of Covalent Binding of Acetaminophen to Human Serum Albumin

โœ Scribed by Damsten, M. C.; Commandeur, J. N. M.; Fidder, A.; Hulst, A. G.; Touw, D.; Noort, D.; Vermeulen, N. P. E.


Book ID
121840421
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2007
Tongue
English
Weight
461 KB
Volume
35
Category
Article
ISSN
0090-9556

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A liquid chromatographic/tandem mass spectrometric (LC/MS/MS) assay was developed for the quantitative determination of olanzapine (LY170053, OLZ) in human plasma and serum. Bond Elut solid-phase extraction C 2 cartridges (single cartridge or 96-well format), in conjunction with a positive pressure